Information about Zofran.

ZOFRAN ODT orally disintegrating tablets are whiteroundand plano-convex tablets available in the following strengths:

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FDA pregnancy category BThis medication is not expected to be harmful to an unborn babyTell your doctor if you are pregnant or plan to become pregnant during treatment.

The development of serotonin syndrome has been reported with 5-HT 3 receptor antagonists aloneMost reports have been associated with concomitant use of serotonergic drugse.gselective serotonin reuptake inhibitorsSSRIsserotonin and norepinephrine reuptake inhibitorsSNRIsmonoamine oxidase inhibitorsmirtazapinefentanyllithiumtramadoland intravenous methylene blueSome of the reported cases were fatalSerotonin syndrome occurring with overdose of ZOFRAN alone has also been reportedThe majority of reports of serotonin syndrome related to 5-HT 3 receptor antagonist use occurred in a post-anesthesia care unit or an infusion center.

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