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If patients present with a suspected nevirapine-associated rashliver function tests should be performedPatients with moderate to severe elevationsASAT or ALAT5 ULNshould be permanently discontinued from nevirapine.

Discontinue if severe rash or any rash accompanied by constitutional findings occurs.

An increase in weight and in levels of blood lipids and glucose may occur during antiretroviral therapySuch changes may in part be linked to disease control and life styleFor lipidsthere is in some cases evidence for a treatment effectwhile for weight gain there is no strong evidence relating this to any particular treatmentFor monitoring of blood lipids and glucose reference is made to established HIV treatment guidelinesLipid disorders should be managed as clinically appropriate.

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additional important information regarding the use of viramune for the treatment of hiv-1 infection .