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Potassium-conserving therapy should also be avoided in severely ill patients in whom respiratory or metabolic acidosis may occurAcidosis may be associated with rapid elevations in serum potassium levelsIf MAXZIDE is employedfrequent evaluations of acid/base balance and serum electrolytes are necessary.

This medication can increase your potassium levelsespecially if you have kidney disease or diabetesor are severely illPotassium levels must be done while you are taking this medicationIf not treatedvery high potassium levels can sometimes be fatalIf you notice any of the following serious side effectstell your doctor right awaymuscle weaknessslow/irregular heartbeat.

In patients requiring hydrochlorothiazide therapy and in whom hypokalemia cannot be risked therapy may be initiated with MAXZIDE-25 MGIf an optimal blood pressure response is not obtained with MAXZIDE-25 MGthe dose should be increased to two MAXZIDE-25 MG tablets daily as a single doseor one MAXZIDE tablet dailyIf blood pressure still is not controlledanother antihypertensive agent may be addedsee PRECAUTIONSDRUG INTERACTIONS

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clearance of lithium by the kidneys is usually successful with certain diuretic medications, including amiloride and triamterene.