Information about Sinemet.

This leaflet answers some common questions about SINEMETIt does not contain all the available information.

All patients should be observed carefully for the development of depression with concomitant suicidal tendencies.

Carbidopa allows patients treated for Parkinson’s disease to use much lower doses of levodopaSome patients who responded poorly to levodopa have improved on SINEMETThis is most likely due to decreased peripheral decarboxylation of levodopa caused by administration of carbidopa rather than by a primary effect of carbidopa on the nervous systemCarbidopa has not been shown to enhance the intrinsic efficacy of levodopa.

The symptoms of Parkinson’s disease are caused by a lack of dopaminea naturally occurring chemical produced by certain brain cellsDopamine relays messages in the part of the brain that controls muscle movement.

If your doctor tells you to stop taking SINEMET or the tablets have passed their expiry dateask your pharmacist what to do with any that are left over.

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in 1991, the merck co pd drug sinemet received federal drug administration fda approval for the treatment of pd.