Information about Imuran.

Store Imuran at room temperatureDO NOT store this medication in direct heat or lightDO NOT store this medication in the bathroomnear the kitchen sinkor in other damp placesHeat or moisture may cause it to break downKeep this drug in the container it came intightly sealedDo not keep outdated medicineKeep this and other drugs out of the reach of children.

WARNING/CAUTIONEven though it may be raresome people may have very bad and sometimes deadly side effects when taking a drugTell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

A gastrointestinal hypersensitivity reaction characterized by severe nausea and vomiting has been reportedThese symptoms may also be accompanied by diarrhearashfevermalaisemyalgiaselevations in liver enzymesand occasionallyhypotensionSymptoms of gastrointestinal toxicity most often develop within the first several weeks of therapy with IMURAN and are reversible upon discontinuation of the drugThe reaction can recur within hours after re-challenge with a single dose of IMURAN.

Renal transplant patients are known to have an increased risk of malignancypredominantly skin cancer and reticulum cell or lymphomatous tumorsThe risk of post-transplant lymphomas may be increased in patients who receive aggressive treatment with immunosuppressive drugsincluding IMURANThereforeimmunosuppressive drug therapy should be maintained at the lowest effective levels.

It is recommended that consideration be given to either genotype or phenotype patients for TPMTPhenotyping and genotyping methods are commercially availableThe most common non-functional alleles associated with reduced levels of TPMT activity are TPMT*2TPMT*3A and TPMT*3CPatients with two nonfunctional alleleshomozygoushave low or absent TPMT activity and those with one non-functional alleleheterozygoushave intermediate activityAccurate phenotypingred blood cell TPMT activityresults are not possible in patients who have received recent blood transfusionsTPMT testing may also be considered in patients with abnormal CBC results that do not respond to dose reductionEarly drug discontinuation in these patients is advisableTPMT TESTING CANNOT SUBSTITUTE FOR COMPLETE BLOOD COUNTCBCMONITORING IN PATIENTS RECEIVING IMURANSee CLINICAL PHARMACOLOGYWARNINGSADVERSE REACTIONS and DOSAGE AND ADMINISTRATION sections.

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if you imuran is nearby, but think about finding another even if you suspect that your ear infection imuran has prandial in for the switch, although i seemed to analyze but about 2 weeks now, and only occurs in about 5 of users.